Depression Treatment Options in San Antonio
Depression is a serious mood disorder that causes persistent feelings of sadness, loss of interest, and decreased energy, significantly affecting daily functioning. From mild situational depression to severe, treatment-resistant major depressive disorder, our San Antonio psychiatrists offer a full spectrum of evidence-based treatments, including personalized medication management, TMS, and ketamine therapy.
Depression Treatment Options at Health 210 Psychiatry
- Comprehensive psychiatric evaluation
- Medication management with expert prescribers
- TMS therapy — FDA-cleared for depression
- Ketamine & Spravato® for treatment-resistant cases
- Coordinated care with therapists and primary care
- Telehealth Appointments Available
More Than Feeling Sad — A Real Medical Condition
Major Depressive Disorder (MDD) is one of the most common and burdensome medical conditions in the world. It is not a character flaw or a sign of weakness — it is a complex brain disorder influenced by genetics, neurochemistry, life experiences, and environment. Depression affects how you think, feel, sleep, eat, and function every single day.
Symptoms can include persistent sadness, loss of interest in activities you once loved, fatigue, difficulty concentrating, changes in sleep and appetite, feelings of worthlessness or guilt, and — in severe cases — thoughts of death or suicide. These symptoms must persist for at least two weeks to meet diagnostic criteria for MDD, and they must significantly impair daily functioning.
The good news: depression is highly treatable. With the right combination of approaches — and a psychiatrist who doesn't give up when the first treatment doesn't work — the vast majority of people with depression can achieve remission and reclaim their lives.
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Our Approach to Treating Depression
We use a systematic, stepwise approach — always starting with a thorough evaluation and escalating to more advanced interventions when standard treatments aren't sufficient.
Step 1: Medication Management
First-line treatment for most forms of depression. SSRIs, SNRIs, bupropion, mirtazapine, tricyclics, and MAOIs — prescribed carefully and monitored closely by board-certified psychiatrists.
Learn MoreStep 2: TMS Therapy
When 1–2 antidepressants haven't worked, FDA-cleared TMS therapy can activate underperforming mood circuits in the brain. Drug-free, non-invasive, and covered by most insurance plans.
Learn MoreStep 3: Spravato® (Esketamine)
FDA-approved for treatment-resistant depression after two failed antidepressant trials. Nasal spray administered in-office, often covered by insurance.
Learn MoreAdvanced: IV/IM Ketamine
For the most severe, treatment-resistant cases — IV and IM ketamine provide rapid relief, sometimes within hours. Particularly valuable in cases involving acute suicidal ideation.
Learn MoreWhat Our Patients Say
"This practice has helped me so much with my mental health. I don't have enough great things to say about the staff and their treatment options. Truly life-changing care."
Depression Treatment — Common Questions
What is treatment-resistant depression?
Treatment-resistant depression (TRD) is generally defined as depression that has not responded adequately to at least two different antidepressant medications, each tried at an adequate dose for an adequate duration (typically 6–8 weeks). Approximately 30% of people with MDD have TRD. We specialize in this population.
How long does depression treatment take?
The timeline varies significantly by individual and treatment type. Antidepressants typically take 4–8 weeks to reach full effect. TMS requires a 6–9 week course. Ketamine can produce effects within hours. Most people with depression require ongoing treatment — the goal is not just acute relief but long-term maintenance of wellness.
Does depression require therapy in addition to medication?
Research consistently shows that the combination of psychiatric medication and psychotherapy is more effective than either alone for moderate-to-severe depression. We work closely with therapists and can provide referrals to licensed counselors and psychologists in San Antonio who complement our psychiatric care.
Is depression covered by my insurance?
Yes — psychiatric evaluation and medication management for depression is covered by all major insurance plans including Aetna, BCBS, Cigna, United Healthcare, Humana, Medicare, and TRICARE. Coverage for TMS and ketamine/Spravato varies. Our team will verify your specific benefits before recommending a treatment plan.
You Don't Have to Live With Depression
Our psychiatric team is here to find the right combination of treatments to help you feel like yourself again.
Health 210 Psychiatry is a proud member of Privia Medical Group — a high-performance physician network committed to coordinated, patient-first care across San Antonio and beyond.
